Educational Levels in Patients with Stargardt Disease

Quantifying fixation in patients with Stargardt disease

Fixational eye movements in 60 eyes of 30 patients with ABCA4-associated Stargardt disease were recorded by a Scanning Laser Ophthalmoscope (SLO). The results were quantified by two new fixation quality measures expressing the eccentricity of the preferred retinal locus (PRL) non-parametrically, and fixation stability by a dynamic index. 46 eyes (77%) fixated eccentrically; in 32 eyes (70% of t...

Low Levels of Triiodothyronine in Patients with Alzheimer’s Disease

Visual Cortex Activation in Patients With Stargardt Disease.

Purpose Primary visual cortex (PVC) contains a retinotopic map in which the central visual field (CVF) is highly magnified compared to the peripheral field. Several studies have used functional magnetic resonance imaging (fMRI) in patients with macular degeneration to assess the reorganization of visual processing in relationship with the development of extrafoveal preferred retinal locus (PRL)...

The effect of light deprivation in patients with Stargardt disease.

PURPOSE To investigate whether long-term protection from light exposure affects the rate of disease progression in patients with autosomal recessive Stargardt disease (STGD1), measured using fundus autofluorescence imaging. DESIGN Longitudinal, retrospective, interventional case series. METHODS Five patients with Stargardt disease protected 1 eye from light exposure by applying a black cont...

Stargardt disease in a patient with retinoblastoma.

Retinoblastoma is the most common primary ocular malignancy of young children, with an incidence of 1:17000 to 1:34000 new births. Retinoblastoma is bilateral in about 30% of cases. Although new modalities offer an enhanced chance of eye salvage, in bilateral disease, management often leads to enucleation of the more-involved eye, with more conservative treatment of the better eye. Subsequently...